Northwestern University Feinberg School of Medicine

Program in Endocrinology, Diabetes and Hormone Action

Publications

Below is a list of publications associated with NUPEDHA.
  1. Sam S, Vellanki P, Yalamanchi SK, Bergman RN, Dunaif A  Exaggerated glucagon responses to hypoglycemia in women with polycystic ovary syndrome.  Metabolism  2017 Jun;71:125-131. pii:S0026-0495(17)30088-4
  2. Gorsic LK, Kosova G, Werstein B, Sisk R, Legro RS, Hayes MG, Teixeira JM, Dunaif A, Urbanek M  Pathogenic Anti-Müllerian Hormone Variants in Polycystic Ovary Syndrome.  J Clin Endocrinol Metab  2017 Aug 01;102(8):2862-2872. doi:10.1210/jc.2017-00612
  3. Kim J, Jin H, Zhao JC, Yang YA, Li Y, Yang X, Dong X, Yu J  FOXA1 inhibits prostate cancer neuroendocrine differentiation.  Oncogene  2017 Jul 13;36(28):4072-4080. doi:10.1038/onc.2017.50
  4. Sandler V, Reisetter AC, Bain JR, Muehlbauer MJ, Nodzenski M, Stevens RD, Ilkayeva O, Lowe LP, Metzger BE, Newgard CB, Scholtens DM, Lowe WL,   Associations of maternal BMI and insulin resistance with the maternal metabolome and newborn outcomes.  Diabetologia  2017 Mar;60(3):518-530. doi:10.1007/s00125-016-4182-2
  5. Fong KW, Zhao JC, Kim J, Li S, Yang YA, Song B, Rittie L, Hu M, Yang X, Perbal B, Yu J  Polycomb-Mediated Disruption of an Androgen Receptor Feedback Loop Drives Castration-Resistant Prostate Cancer.  Cancer Res  2017 Jan 15;77(2):412-422. doi:10.1158/0008-5472.CAN-16-1949
  6. Ludvik AE, Pusec CM, Priyadarshini M, Angueira AR, Guo C, Lo A, Hershenhouse KS, Yang GY, Ding X, Reddy TE, Lowe WL, Layden BT  HKDC1 Is a Novel Hexokinase Involved in Whole-Body Glucose Use.  Endocrinology  2016 Sep;157(9):3452-61. doi:10.1210/en.2016-1288
  7. Villa SR, Priyadarshini M, Fuller MH, Bhardwaj T, Brodsky MR, Angueira AR, Mosser RE, Carboneau BA, Tersey SA, Mancebo H, Gilchrist A, Mirmira RG, Gannon M, Layden BT  Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival.  Sci Rep  2016 Jun 21;6:28159. doi:10.1038/srep28159
  8. Navarro G, Xu W, Jacobson DA, Wicksteed B, Allard C, Zhang G, De Gendt K, Kim SH, Wu H, Zhang H, Verhoeven G, Katzenellenbogen JA, Mauvais-Jarvis F  Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male.  Cell Metab  2016 May 10;23(5):837-51. doi:10.1016/j.cmet.2016.03.015
  9. Dapas M, Kandpal M, Bi Y, Davuluri RV  Comparative evaluation of isoform-level gene expression estimation algorithms for RNA-seq and exon-array platforms.  Brief Bioinform  2017 03 01;18(2):260-269. doi:10.1093/bib/bbw016
  10. Bartlett CS, Jeansson M, Quaggin SE  Vascular Growth Factors and Glomerular Disease.  Annu Rev Physiol  2016;78:437-61. doi:10.1146/annurev-physiol-021115-105412
  11. Monsivais D, Dyson MT, Yin P, Navarro A, Coon JS, Pavone ME, Bulun SE  Estrogen receptor β regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activation.  Fertil Steril  2016 05;105(5):1266-1273. pii:S0015-0282(16)00047-9
  12. Perelis M, Marcheva B, Ramsey KM, Schipma MJ, Hutchison AL, Taguchi A, Peek CB, Hong H, Huang W, Omura C, Allred AL, Bradfield CA, Dinner AR, Barish GD, Bass J  Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion.  Science  2015 Nov 06;350(6261):aac4250. doi:10.1126/science.aac4250
  13. Dyson MT, Kakinuma T, Pavone ME, Monsivais D, Navarro A, Malpani SS, Ono M, Bulun SE  Aberrant expression and localization of deoxyribonucleic acid methyltransferase 3B in endometriotic stromal cells.  Fertil Steril  2015 Oct;104(4):953-963.e2. pii:S0015-0282(15)00475-6
  14. Priyadarshini M, Villa SR, Fuller M, Wicksteed B, Mackay CR, Alquier T, Poitout V, Mancebo H, Mirmira RG, Gilchrist A, Layden BT  An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion.  Mol Endocrinol  2015 Jul;29(7):1055-66. doi:10.1210/me.2015-1007
  15. Yin P, Ono M, Moravek MB, Coon JS, Navarro A, Monsivais D, Dyson MT, Druschitz SA, Malpani SS, Serna VA, Qiang W, Chakravarti D, Kim JJ, Bulun SE  Human uterine leiomyoma stem/progenitor cells expressing CD34 and CD49b initiate tumors in vivo.  J Clin Endocrinol Metab  2015 Apr;100(4):E601-6. doi:10.1210/jc.2014-2134
  16. Guo C, Ludvik AE, Arlotto ME, Hayes MG, Armstrong LL, Scholtens DM, Brown CD, Newgard CB, Becker TC, Layden BT, Lowe WL, Reddy TE  Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1.  Nat Commun  2015 Feb 04;6:6069. doi:10.1038/ncomms7069
  17. Vellanki P, Umpierrez GE  Iatrogenic hypoglycemia and quality of life in patients with type 2 diabetes mellitus.  Rev Clin Esp  2015 Mar;215(2):104-6. doi:10.1016/j.rce.2014.11.017
  18. Angueira AR, Ludvik AE, Reddy TE, Wicksteed B, Lowe WL, Layden BT  New insights into gestational glucose metabolism: lessons learned from 21st century approaches.  Diabetes  2015 Feb;64(2):327-34. doi:10.2337/db14-0877
  19. Moravek MB, Yin P, Ono M, Coon JS, Dyson MT, Navarro A, Marsh EE, Chakravarti D, Kim JJ, Wei JJ, Bulun SE  Ovarian steroids, stem cells and uterine leiomyoma: therapeutic implications.  Hum Reprod Update  ;21(1):1-12. doi:10.1093/humupd/dmu048
  20. Navarro A, Yin P, Ono M, Monsivais D, Moravek MB, Coon JS, Dyson MT, Wei JJ, Bulun SE  5-Hydroxymethylcytosine promotes proliferation of human uterine leiomyoma: a biological link to a new epigenetic modification in benign tumors.  J Clin Endocrinol Metab  2014 Nov;99(11):E2437-45. doi:10.1210/jc.2014-2264
  21. Monsivais D, Dyson MT, Yin P, Coon JS, Navarro A, Feng G, Malpani SS, Ono M, Ercan CM, Wei JJ, Pavone ME, Su E, Bulun SE  ERβ- and prostaglandin E2-regulated pathways integrate cell proliferation via Ras-like and estrogen-regulated growth inhibitor in endometriosis.  Mol Endocrinol  2014 Aug;28(8):1304-15. doi:10.1210/me.2013-1421
  22. Eren M, Boe AE, Murphy SB, Place AT, Nagpal V, Morales-Nebreda L, Urich D, Quaggin SE, Budinger GR, Mutlu GM, Miyata T, Vaughan DE  PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.  Proc Natl Acad Sci U S A  2014 May 13;111(19):7090-5. doi:10.1073/pnas.1321942111
  23. Dyson MT, Roqueiro D, Monsivais D, Ercan CM, Pavone ME, Brooks DC, Kakinuma T, Ono M, Jafari N, Dai Y, Bulun SE  Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in endometriosis.  PLoS Genet  2014 Mar;10(3):e1004158. doi:10.1371/journal.pgen.1004158
  24. Mapes B, Chase M, Hong E, Ludvik A, Ceryes K, Huang Y, Kupfer SS  Ex vivo culture of primary human colonic tissue for studying transcriptional responses to 1α,25(OH)2 and 25(OH) vitamin D.  Physiol Genomics  2014 Apr 15;46(8):302-8. doi:10.1152/physiolgenomics.00194.2013
  25. Ono M, Yin P, Navarro A, Moravek MB, Coon V JS, Druschitz SA, Gottardi CJ, Bulun SE  Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth.  Fertil Steril  2014 May;101(5):1441-9. doi:10.1016/j.fertnstert.2014.01.017
  26. Moy I, Todorović V, Dubash AD, Coon JS, Parker JB, Buranapramest M, Huang CC, Zhao H, Green KJ, Bulun SE  Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cells.  Oncogene  2015 Jan 15;34(3):323-33. doi:10.1038/onc.2013.553
  27. Vellanki P, Lange K, Elaraj D, Kopp PA, El Muayed M  Denosumab for management of parathyroid carcinoma-mediated hypercalcemia.  J Clin Endocrinol Metab  2014 Feb;99(2):387-90. doi:10.1210/jc.2013-3031
  28. Ono M, Yin P, Navarro A, Moravek MB, Coon JS, Druschitz SA, Serna VA, Qiang W, Brooks DC, Malpani SS, Ma J, Ercan CM, Mittal N, Monsivais D, Dyson MT, Yemelyanov A, Maruyama T, Chakravarti D, Kim JJ, Kurita T, Gottardi CJ, Bulun SE  Paracrine activation of WNT/β-catenin pathway in uterine leiomyoma stem cells promotes tumor growth.  Proc Natl Acad Sci U S A  2013 Oct 15;110(42):17053-8. doi:10.1073/pnas.1313650110
  29. Peek CB, Affinati AH, Ramsey KM, Kuo HY, Yu W, Sena LA, Ilkayeva O, Marcheva B, Kobayashi Y, Omura C, Levine DC, Bacsik DJ, Gius D, Newgard CB, Goetzman E, Chandel NS, Denu JM, Mrksich M, Bass J  Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice.  Science  2013 Nov 01;342(6158):1243417. doi:10.1126/science.1243417
  30. Ramsey KM, Affinati AH, Peek CB, Marcheva B, Hong HK, Bass J  Circadian measurements of sirtuin biology.  Methods Mol Biol  2013;1077:285-302. doi:10.1007/978-1-62703-637-5_19
  31. Ma JJ, Monsivais D, Dyson MT, Coon JS, Malpani S, Ono M, Zhao H, Xin H, Pavone ME, Kim JJ, Chakravarti D, Bulun SE  Ligand-activated peroxisome proliferator-activated receptor β/δ modulates human endometrial cancer cell survival.  Horm Cancer  2013 Dec;4(6):358-70. doi:10.1007/s12672-013-0157-7
  32. Marcheva B, Ramsey KM, Peek CB, Affinati A, Maury E, Bass J  Circadian clocks and metabolism.  Handb Exp Pharmacol  2013;(217):127-55. doi:10.1007/978-3-642-25950-0_6
  33. Sasidevi A, Vellanki P, Kunselman AR, Raja-Khan N, Dunaif A, Legro RS  Familial aggregation of circulating C-reactive protein in polycystic ovary syndrome.  Hum Reprod  2013 Mar;28(3):770-6. doi:10.1093/humrep/des416
  34. Liu S, Kilic G, Meyers MS, Navarro G, Wang Y, Oberholzer J, Mauvais-Jarvis F  Oestrogens improve human pancreatic islet transplantation in a mouse model of insulin deficient diabetes.  Diabetologia  2013 Feb;56(2):370-81. doi:10.1007/s00125-012-2764-1
  35. Toft DJ, Moyer TJ, Standley SM, Ruff Y, Ugolkov A, Stupp SI, Cryns VL  Coassembled cytotoxic and pegylated peptide amphiphiles form filamentous nanostructures with potent antitumor activity in models of breast cancer.  ACS Nano  2012 Sep 25;6(9):7956-65
  36. Dyson MT, Bulun SE  Cutting SRC-1 down to size in endometriosis.  Nat Med  2012 Jul 06;18(7):1016-8. doi:10.1038/nm.2855
  37. Tiano JP, Mauvais-Jarvis F  Molecular mechanisms of estrogen receptors' suppression of lipogenesis in pancreatic β-cells.  Endocrinology  2012 Jul;153(7):2997-3005. doi:10.1210/en.2011-1980
  38. Tiano J, Mauvais-Jarvis F  Selective estrogen receptor modulation in pancreatic β-cells and the prevention of type 2 diabetes.  Islets  ;4(2):173-6. doi:10.4161/isl.19747
  39. Monsivais D, Bray JD, Su E, Pavone ME, Dyson MT, Navarro A, Kakinuma T, Bulun SE  Activated glucocorticoid and eicosanoid pathways in endometriosis.  Fertil Steril  2012 Jul;98(1):117-25. doi:10.1016/j.fertnstert.2012.03.030
  40. Navarro A, Yin P, Monsivais D, Lin SM, Du P, Wei JJ, Bulun SE  Genome-wide DNA methylation indicates silencing of tumor suppressor genes in uterine leiomyoma.  PLoS One  2012;7(3):e33284. doi:10.1371/journal.pone.0033284
  41. Peek CB, Ramsey KM, Marcheva B, Bass J  Nutrient sensing and the circadian clock.  Trends Endocrinol Metab  2012 Jul;23(7):312-8. doi:10.1016/j.tem.2012.02.003
  42. Tiano JP, Mauvais-Jarvis F  Importance of oestrogen receptors to preserve functional β-cell mass in diabetes.  Nat Rev Endocrinol  2012 Feb 14;8(6):342-51. doi:10.1038/nrendo.2011.242
  43. Yalamanchi SK, Sam S, Cardenas MO, Holaday LW, Urbanek M, Dunaif A  Association of fibrillin-3 and transcription factor-7-like 2 gene variants with metabolic phenotypes in PCOS.  Obesity (Silver Spring)  2012 Jun;20(6):1273-8. doi:10.1038/oby.2011.400
  44. Rink JS, Chen X, Zhang X, Kaufman DB  Conditional and specific inhibition of NF-κB in mouse pancreatic β cells prevents cytokine-induced deleterious effects and improves islet survival posttransplant.  Surgery  2012 Feb;151(2):330-9. doi:10.1016/j.surg.2011.07.011